Assay Detail
Functional
CHEMBL693416
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Inhibitory concentration in HeLa cells
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Discovery, characterization, and structure-activity relationships studies of proapoptotic polyphenols targeting B-cell lymphocyte/leukemia-2 proteins.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.66 | 5.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL66953 | PURPUROGALLIN | — | 1 | 5.19 |
| CHEMBL339835 | — | — | 1 | 4.64 |
| CHEMBL334615 | — | — | 1 | 4.52 |
| CHEMBL135650 | — | — | 1 | 4.29 |
| CHEMBL133255 | — | — | 1 | - |
| CHEMBL134871 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL66953 | PURPUROGALLIN | IC50 | = | 6500.0 | nM | 5.19 |
| CHEMBL339835 | — | IC50 | = | 22900.0 | nM | 4.64 |
| CHEMBL334615 | — | IC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL135650 | — | IC50 | = | 51500.0 | nM | 4.29 |
| CHEMBL133255 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL134871 | — | IC50 | > | 100000.0 | nM | - |