Assay Detail
Functional
CHEMBL693435
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effective concentration of compound for transcriptional activation of PGE-2 in Human cell native protein assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Cell line |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Differentiation of in vitro transcriptional repression and activation profiles of selective glucocorticoid modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 8.14 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL131 | PREDNISOLONE | 4.0 | 1 | 8.70 |
| CHEMBL298687 | — | — | 1 | 8.27 |
| CHEMBL46325 | — | — | 1 | 7.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL131 | PREDNISOLONE | EC50 | = | 2.0 | nM | 8.70 |
| CHEMBL298687 | — | EC50 | = | 5.4 | nM | 8.27 |
| CHEMBL46325 | — | EC50 | = | 35.0 | nM | 7.46 |