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Assay Detail

CHEMBL693667

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Concentration to reduce vaccinia virus plaque reduction (VPR) by 50% in HFF cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HFF
Confidence 1 — Organism
Curated By Intermediate

Target

HFF (CHEMBL614071)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis and biological evaluation of 5-substituted derivatives of the potent antiherpes agent (north)-methanocarbathymine.
Russ P, Schelling P, Scapozza L, Folkers G, Clercq ED, Marquez VE.
J Med Chem (2003) 46 : 5045 -5054
PubMed 14584954 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.09 5.09

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL413063 1 5.09

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL413063 EC50 = 8190.0 nM 5.09