Assay Detail
Functional
CHEMBL693866
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Compound was tested in vitro to mobilize calcium from HT-29 cells
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HT-29 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Reduced amide bond neurotensin 813 mimetics with potent in vivo activity
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 6.68 | 8.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL342252 | — | — | 1 | 8.38 |
| CHEMBL427604 | — | — | 1 | 6.96 |
| CHEMBL269601 | — | — | 1 | 6.44 |
| CHEMBL6508 | — | — | 1 | 6.29 |
| CHEMBL6562 | — | — | 1 | 5.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL342252 | — | EC50 | = | 4.21 | nM | 8.38 |
| CHEMBL427604 | — | EC50 | = | 110.0 | nM | 6.96 |
| CHEMBL269601 | — | EC50 | = | 362.0 | nM | 6.44 |
| CHEMBL6508 | — | EC50 | = | 512.0 | nM | 6.29 |
| CHEMBL6562 | — | EC50 | = | 4505.0 | nM | 5.35 |