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Assay Detail

CHEMBL694024

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
In vitro effective concentration in normal human dermal fibroblasts
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Triterpene and diterpene inhibitors of pyruvate dehydrogenase kinase (PDK).
Aicher TD, Damon RE, Koletar J, Vinluan CC, Brand LJ, Gao J, Shetty SS, Kaplan EL, Mann WR.
Bioorg Med Chem Lett (1999) 9 : 2223 -2228
PubMed 10465550 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 4.89 5.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL440684 1 5.77
CHEMBL13960 DICHLOROACETIC ACID 3.0 1 4.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL440684 EC50 = 1700.0 nM 5.77
CHEMBL13960 DICHLOROACETIC ACID EC50 = 100000.0 nM 4.00