Assay Detail
Functional
CHEMBL694824
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro Antineoplastic Activity against Human non small cell lung carcinoma A549 Cell lines
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and evaluation of analogues of 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxyadenosine as inhibitors of tumor cell growth, trypanosomal growth, and HIV-1 infectivity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.52 | 5.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL381751 | — | — | 1 | 5.52 |
| CHEMBL608951 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL381751 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL608951 | — | IC50 | > | 100000.0 | nM | - |