Assay Detail
Functional
CHEMBL694909
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for growth inhibitory activity against Hep2 tumor cell lines
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HEp-2 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Novel pyrimidine and purine derivatives of L-ascorbic acid: synthesis and biological evaluation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 4.46 | 5.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL90871 | — | — | 1 | 5.00 |
| CHEMBL88434 | — | — | 1 | 4.70 |
| CHEMBL327570 | — | — | 1 | 4.70 |
| CHEMBL91024 | — | — | 1 | 4.40 |
| CHEMBL92041 | — | — | 1 | 4.40 |
| CHEMBL88616 | — | — | 1 | 4.22 |
| CHEMBL419504 | — | — | 1 | 4.22 |
| CHEMBL328116 | — | — | 1 | 4.05 |
| CHEMBL315331 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL90871 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL88434 | — | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL327570 | — | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL91024 | — | IC50 | = | 40000.0 | nM | 4.40 |
| CHEMBL92041 | — | IC50 | = | 40000.0 | nM | 4.40 |
| CHEMBL88616 | — | IC50 | = | 60000.0 | nM | 4.22 |
| CHEMBL419504 | — | IC50 | = | 60000.0 | nM | 4.22 |
| CHEMBL328116 | — | IC50 | = | 90000.0 | nM | 4.05 |
| CHEMBL315331 | — | IC50 | > | 100000.0 | nM | - |