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Assay Detail

CHEMBL695157

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Functional
Histamine H1 receptor antagonistic activity on the isolated guinea pig ileum determined by Schild plot.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Cavia porcellus
Tissue Ileum
Confidence 9 — Direct single protein target
Curated By Intermediate

Target

Histamine H1 receptor (CHEMBL3943)
Type SINGLE PROTEIN
Organism Cavia porcellus

Publication

Iodoaminopotentidine and related compounds: a new class of ligands with high affinity and selectivity for the histamine H2 receptor.
Hirschfeld J, Buschauer A, Elz S, Schunack W, Ruat M, Traiffort E, Schwartz JC.
J Med Chem (1992) 35 : 2231 -2238
PubMed 1613748 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 5.80 5.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL70746 1 5.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL70746 Kd = 1584.89 nM 5.80