Assay Detail
Binding
CHEMBL695159
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Potency at histamine H1 receptor subtype, was tested on guinea pig right ileum
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Tissue | Ileum |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
Novel nonimidazole histamine H3 receptor antagonists: 1-(4-(phenoxymethyl)benzyl)piperidines and related compounds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 5.23 | 5.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL35869 | — | — | 1 | 5.46 |
| CHEMBL39603 | — | — | 1 | 5.34 |
| CHEMBL39716 | — | — | 1 | 5.10 |
| CHEMBL290613 | — | — | 1 | 5.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL35869 | — | Kd | = | 3467.37 | nM | 5.46 |
| CHEMBL39603 | — | Kd | = | 4570.88 | nM | 5.34 |
| CHEMBL39716 | — | Kd | = | 7943.28 | nM | 5.10 |
| CHEMBL290613 | — | Kd | = | 9332.54 | nM | 5.03 |