Assay Detail

CHEMBL695673

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Functional

Compound was evaluated for cytotoxic activity against HeLa S3 cell line

ChEMBL ↗

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Target

HeLa (CHEMBL399) ↗

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Primary target HeLa

CHEMBL399

Anchored from Assay target.

Protein identity HeLa

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	HeLa
Confidence	1 — Organism
Curated By	Intermediate

Target

HeLa (CHEMBL399) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Potent antimitotic and cell growth inhibitory properties of substituted chalcones.

Ducki S, Forrest R, Hadfield JA, Kendall A, Lawrence NJ, McGown AT, Rennison D.
Bioorg Med Chem Lett (1998) 8 : 1051 -1056
PubMed 9871706 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	9.21	9.21

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL9859	—	—	1	9.21

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL9859	—	IC50	=	0.62	nM	9.21