Assay Detail
Functional
CHEMBL696036
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Compound was tested against HFF cells infected with herpes simplex virus type 2 (HSV-2) by cytopathic effect inhibition assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HFF |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
(Z)- and (E)-2-((hydroxymethyl)cyclopropylidene)methyladenine and -guanine. New nucleoside analogues with a broad-spectrum antiviral activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.97 | 4.97 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL305612 | — | — | 1 | 4.97 |
| CHEMBL306257 | SYNGUANOL | — | 1 | - |
| CHEMBL75950 | — | — | 1 | - |
| CHEMBL75956 | — | — | 1 | - |
| CHEMBL76121 | — | — | 1 | - |
| CHEMBL74478 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL305612 | — | IC50 | = | 10600.0 | nM | 4.97 |
| CHEMBL306257 | SYNGUANOL | IC50 | > | 413000.0 | nM | - |
| CHEMBL75950 | — | IC50 | > | 79500.0 | nM | - |
| CHEMBL75956 | — | IC50 | > | 413000.0 | nM | - |
| CHEMBL76121 | — | IC50 | > | 79500.0 | nM | - |
| CHEMBL74478 | — | IC50 | = | 395000.0 | nM | - |