Assay Detail
Binding
CHEMBL696315
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested in vitro for the inhibitory activity against human HePTP360 (Hematopoietic protein tyrosine phosphatase)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
PTP1B inhibition and antihyperglycemic activity in the ob/ob mouse model of novel 11-arylbenzo[b]naphtho[2,3-d]furans and 11-arylbenzo[b]naphtho[2,3-d]thiophenes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.63 | 5.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL324232 | — | — | 1 | 5.68 |
| CHEMBL108721 | — | — | 1 | 5.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL324232 | — | IC50 | = | 2100.0 | nM | 5.68 |
| CHEMBL108721 | — | IC50 | = | 2700.0 | nM | 5.57 |