Assay Detail
Functional
CHEMBL696507
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Tested for its concentration necessary to achieve a 50% reduction in absolute cell number compared to vehicle-treated controls using human sebaceous cell assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
A conformationally defined 6-s-trans-retinoic acid isomer: synthesis, chemopreventive activity, and toxicity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.00 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL547 | ISOTRETINOIN | 4.0 | 1 | 7.00 |
| CHEMBL333032 | — | — | 1 | 7.00 |
| CHEMBL2111790 | — | — | 1 | 7.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL547 | ISOTRETINOIN | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL333032 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL2111790 | — | IC50 | = | 100.0 | nM | 7.00 |