Assay Detail
Functional
CHEMBL696949
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Antiviral activity in Human Cytomegalovirus Viral infection was evaluated by ELISA method
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human betaherpesvirus 5 |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Synthesis of non-nucleoside analogs of toyocamycin, sangivamycin, and ++thiosangivamycin: influence of various 7-substituents on antiviral activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.82 | 6.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL172389 | — | — | 1 | 6.82 |
| CHEMBL172213 | — | — | 1 | 6.48 |
| CHEMBL170107 | — | — | 1 | 6.30 |
| CHEMBL368561 | — | — | 1 | 5.75 |
| CHEMBL117969 | — | — | 1 | 5.72 |
| CHEMBL116194 | — | — | 1 | 5.16 |
| CHEMBL171253 | — | — | 1 | 4.50 |
| CHEMBL48444 | — | — | 1 | - |
| CHEMBL300084 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL172389 | — | IC50 | = | 150.0 | nM | 6.82 |
| CHEMBL172213 | — | IC50 | = | 330.0 | nM | 6.48 |
| CHEMBL170107 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL368561 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL117969 | — | IC50 | = | 1900.0 | nM | 5.72 |
| CHEMBL116194 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL171253 | — | IC50 | = | 32000.0 | nM | 4.50 |
| CHEMBL48444 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL300084 | — | IC50 | > | 100000.0 | nM | - |