Assay Detail
Functional
CHEMBL697021
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of radiolabeled fibrinogen binding to activated human platelets.
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Design of a new class of orally active fibrinogen receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 7.77 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL419115 | — | — | 1 | 8.00 |
| CHEMBL309250 | — | — | 1 | 7.96 |
| CHEMBL82264 | — | — | 1 | 7.77 |
| CHEMBL315465 | — | — | 1 | 7.66 |
| CHEMBL84435 | — | — | 1 | 7.66 |
| CHEMBL82231 | — | — | 1 | 7.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL419115 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL309250 | — | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL82264 | — | IC50 | = | 17.0 | nM | 7.77 |
| CHEMBL315465 | — | IC50 | = | 22.0 | nM | 7.66 |
| CHEMBL84435 | — | IC50 | = | 22.0 | nM | 7.66 |
| CHEMBL82231 | — | IC50 | = | 28.0 | nM | 7.55 |