Assay Detail
Binding
CHEMBL697133
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Inhibition of histamine H2 receptor
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
From hit to lead. Analyzing structure-profile relationships.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.00 | 6.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL116463 | — | — | 1 | 6.43 |
| CHEMBL113956 | — | — | 1 | 6.12 |
| CHEMBL326263 | — | — | 1 | 5.99 |
| CHEMBL325516 | — | — | 1 | 5.90 |
| CHEMBL116735 | — | — | 1 | 5.87 |
| CHEMBL117537 | — | — | 1 | 5.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL116463 | — | IC50 | = | 368.0 | nM | 6.43 |
| CHEMBL113956 | — | IC50 | = | 757.0 | nM | 6.12 |
| CHEMBL326263 | — | IC50 | = | 1030.0 | nM | 5.99 |
| CHEMBL325516 | — | IC50 | = | 1250.0 | nM | 5.90 |
| CHEMBL116735 | — | IC50 | = | 1340.0 | nM | 5.87 |
| CHEMBL117537 | — | IC50 | = | 1980.0 | nM | 5.70 |