Assay Detail
Binding
CHEMBL697192
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity against Ins(4,5)P2 receptor prepared from purified guinea pig hepatocytes
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Cell Type | Hepatocyte |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Target
Inositol 1,4,5-trisphosphate receptor (CHEMBL2111451) ↗| Type | PROTEIN FAMILY |
| Organism | Homo sapiens |
Publication
Synthesis and binding properties of myo-inositol 4,5,6-tris(phosphate) an analogue of myo-inositol 1,4,5-tris(phosphate). Correlation with the ionization state of the molecules
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.30 | 4.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL21825 | — | — | 1 | 4.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL21825 | — | IC50 | = | 50000.0 | nM | 4.30 |