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Assay Detail

CHEMBL697193

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity against Ins(4,5)P2 receptor in swiss 3T3 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Cell Type NIH3T3
Confidence 4 — Cell-line / Tissue
Curated By Intermediate

Target

Inositol 1,4,5-trisphosphate receptor (CHEMBL2111451)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

Synthesis and binding properties of myo-inositol 4,5,6-tris(phosphate) an analogue of myo-inositol 1,4,5-tris(phosphate). Correlation with the ionization state of the molecules
Schmitt L, Spiess B, Schlewer G
Bioorg Med Chem Lett (1995) 5 : 1225 -1230
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.70 4.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL21825 1 4.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL21825 IC50 = 20000.0 nM 4.70