Assay Detail
Binding
CHEMBL697248
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Inhibitory concentration against isolated Histone deacetylase
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Histone deacetylase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 6.36 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL150237 | — | — | 1 | 8.70 |
| CHEMBL83747 | PSAMMAPLIN A | — | 1 | 8.40 |
| CHEMBL343476 | PSAMMAPLIN D | — | 1 | 7.36 |
| CHEMBL147134 | — | — | 1 | 7.10 |
| CHEMBL150236 | PSAMMAPLIN E | — | 1 | 6.48 |
| CHEMBL146677 | — | — | 1 | 4.64 |
| CHEMBL149249 | — | — | 1 | 4.16 |
| CHEMBL146251 | — | — | 1 | 4.07 |
| CHEMBL149765 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL150237 | — | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL83747 | PSAMMAPLIN A | IC50 | = | 4.0 | nM | 8.40 |
| CHEMBL343476 | PSAMMAPLIN D | IC50 | = | 44.0 | nM | 7.36 |
| CHEMBL147134 | — | IC50 | = | 79.0 | nM | 7.10 |
| CHEMBL150236 | PSAMMAPLIN E | IC50 | = | 330.0 | nM | 6.48 |
| CHEMBL146677 | — | IC50 | = | 23000.0 | nM | 4.64 |
| CHEMBL149249 | — | IC50 | = | 70000.0 | nM | 4.16 |
| CHEMBL146251 | — | IC50 | = | 85000.0 | nM | 4.07 |
| CHEMBL149765 | — | IC50 | = | 104000.0 | nM | - |