Assay Detail
Binding
CHEMBL697284
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Inhibitory activity afgainst maize Histone deacetylase 1-A
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Zea mays |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Discovery of (aryloxopropenyl)pyrrolyl hydroxyamides as selective inhibitors of class IIa histone deacetylase homologue HD1-A.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 6.79 | 9.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL99 | TRICHOSTATIN | 1.0 | 1 | 9.10 |
| CHEMBL142441 | — | — | 1 | 7.30 |
| CHEMBL145116 | — | — | 1 | 7.22 |
| CHEMBL415533 | — | — | 1 | 6.70 |
| CHEMBL145685 | — | — | 1 | 6.70 |
| CHEMBL98 | VORINOSTAT | 4.0 | 1 | 6.70 |
| CHEMBL145028 | — | — | 1 | 6.40 |
| CHEMBL145099 | — | — | 1 | 6.30 |
| CHEMBL145531 | — | — | 1 | 4.73 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL99 | TRICHOSTATIN | IC50 | = | 0.8 | nM | 9.10 |
| CHEMBL142441 | — | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL145116 | — | IC50 | = | 60.0 | nM | 7.22 |
| CHEMBL415533 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL145685 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL98 | VORINOSTAT | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL145028 | — | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL145099 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL145531 | — | IC50 | = | 18600.0 | nM | 4.73 |