Assay Detail
Functional
CHEMBL697357
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Compound was evaluated for cell growth inhibition against HeLa cell line by irradiation in the presence of examined compound
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
4'-Methyl derivatives of 5-MOP and 5-MOA: synthesis, photoreactivity, and photobiological activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.61 | 5.97 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL137912 | — | — | 1 | 5.97 |
| CHEMBL140895 | — | — | 1 | 5.90 |
| CHEMBL139186 | — | — | 1 | 5.75 |
| CHEMBL416 | METHOXSALEN | 4.0 | 1 | 5.50 |
| CHEMBL141006 | — | — | 1 | 5.37 |
| CHEMBL139357 | — | — | 1 | 5.17 |
| CHEMBL141690 | ISOBERGAPTENE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL137912 | — | IC50 | = | 1060.0 | nM | 5.97 |
| CHEMBL140895 | — | IC50 | = | 1260.0 | nM | 5.90 |
| CHEMBL139186 | — | IC50 | = | 1760.0 | nM | 5.75 |
| CHEMBL416 | METHOXSALEN | IC50 | = | 3160.0 | nM | 5.50 |
| CHEMBL141006 | — | IC50 | = | 4230.0 | nM | 5.37 |
| CHEMBL139357 | — | IC50 | = | 6830.0 | nM | 5.17 |
| CHEMBL141690 | ISOBERGAPTENE | IC50 | > | 10000.0 | nM | - |