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Assay Detail

CHEMBL697423

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Effective concentration required for evoking response in HEK293 cell
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Cell Type HEK293
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Glutamate receptor ionotropic, kainate 1 (CHEMBL1918)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

4-Alkyl- and 4-cinnamylglutamic acid analogues are potent GluR5 kainate receptor agonists.
Pedregal C, Collado I, Escribano A, Ezquerra J, Domínguez C, Mateo AI, Rubio A, Baker SR, Goldsworthy J, Kamboj RK, Ballyk BA, Hoo K, Bleakman D.
J Med Chem (2000) 43 : 1958 -1968
PubMed 10821708 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.35 5.35

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL294139 1 5.35

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL294139 EC50 = 4500.0 nM 5.35