Assay Detail
Binding
CHEMBL698077
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity of compound was determined against Ionotropic glutamate receptor ionotropic kainate 1 using cell membranes prepared from HEK293 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | HEK293 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Target
Glutamate receptor ionotropic, kainate 1 (CHEMBL1918) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
4-Alkylidenyl glutamic acids, potent and selective GluR5 agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 7.26 | 7.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL299180 | — | — | 1 | 7.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL299180 | — | Ki | = | 54.4 | nM | 7.26 |