Assay Detail

CHEMBL698347

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Antiviral activity in HIV-1GB8 infected JM cells

ChEMBL ↗

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Target

JM1 (CHEMBL614589) ↗

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Primary target JM1

CHEMBL614589

Anchored from Assay target.

Protein identity JM1

Disease frame Disease evidence pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	JM1
Confidence	1 — Organism
Curated By	Intermediate

Target

JM1 (CHEMBL614589) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

HIV protease: a novel chemotherapeutic target for AIDS.

Huff JR.
J Med Chem (1991) 34 : 2305 -2314
PubMed 1875332 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	8.60	8.60

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL3350201	—	—	1	8.60

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL3350201	—	IC50	=	2.5	nM	8.60