Assay Detail
Binding
CHEMBL698451
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Dissociation constant was determined against H1 receptor of guinea pig lung membranes using radioligand binding assays.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Tissue | Lung |
| Confidence | 9 — Direct single protein target |
| Curated By | Intermediate |
Publication
(Piperidinylalkoxy)chromones: novel antihistamines with additional antagonistic activity against leukotriene D4.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 7.84 | 8.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL79732 | — | — | 1 | 8.22 |
| CHEMBL17157 | TERFENADINE | 4.0 | 1 | 7.45 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL79732 | — | Kd | = | 5.98 | nM | 8.22 |
| CHEMBL17157 | TERFENADINE | Kd | = | 35.48 | nM | 7.45 |