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Assay Detail

CHEMBL698511

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory activity against Inosine-5'-monophosphate dehydrogenase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Inosine-5'-monophosphate dehydrogenase (IMPDH) (CHEMBL2111369)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

Discovery of novel low molecular weight inhibitors of IMPDH via virtual needle screening.
Pickett SD, Sherborne BS, Wilkinson T, Bennett J, Borkakoti N, Broadhurst M, Hurst D, Kilford I, McKinnell M, Jones PS.
Bioorg Med Chem Lett (2003) 13 : 1691 -1694
PubMed 12729643 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.60 6.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1207374 1 6.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1207374 Ki = 250.0 nM 6.60