Assay Detail
Functional
CHEMBL698534
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human platelet aggregation mediated by alpha llb/beta3 interaction with fibrinogen
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and solution conformation of cyclo[RGDRGD]: a cyclic peptide with selectivity for the alpha V beta 3 receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.70 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2370493 | — | — | 1 | 7.70 |
| CHEMBL343122 | — | — | 1 | - |
| CHEMBL141005 | — | — | 1 | - |
| CHEMBL411941 | CYCLORGDFV | — | 1 | - |
| CHEMBL343123 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2370493 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL343122 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL141005 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL411941 | CYCLORGDFV | IC50 | > | 100000.0 | nM | - |
| CHEMBL343123 | — | IC50 | > | 100000.0 | nM | - |