Assay Detail
Functional
CHEMBL698625
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In vitro anticellular activity expressed as inhibitory concentration for the growth of human uterine cervix carcinoma HeLa S3 cells for a period of 1 hour
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and antitumor activity of duocarmycin derivatives: A-ring pyrrole compounds bearing cinnamoyl groups.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.71 | 8.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL369203 | — | — | 1 | 8.89 |
| CHEMBL176802 | — | — | 1 | 8.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL369203 | — | IC50 | = | 1.3 | nM | 8.89 |
| CHEMBL176802 | — | IC50 | = | 3.0 | nM | 8.52 |