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Assay Detail

CHEMBL698673

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Functional
compound was tested in vitro for anti HBV activity in HepG2 2.2.15 cells
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HepG2
Confidence 1 — Organism
Curated By Intermediate

Target

HepG2 (CHEMBL395)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis and anti-hepatitis B virus activity of 9-(2-deoxy-2-fluoro-beta-L-arabinofuranosyl) purine nucleosides.
Ma T, Lin JS, Newton MG, Cheng YC, Chu CK.
J Med Chem (1997) 40 : 2750 -2754
PubMed 9276020 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 10 5.46 5.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL309579 2'-BETA-FLUORO-2',3'-DEOXYADENOSINE 1 5.82
CHEMBL3143525 1 5.10
CHEMBL3143553 1 -
CHEMBL3142653 1 -
CHEMBL3142980 1 -
CHEMBL3142650 1 -
CHEMBL3143549 F-ARAG 1.0 1 -
CHEMBL3143557 1 -
CHEMBL3142654 1 -
CHEMBL3142651 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL309579 2'-BETA-FLUORO-2',3'-DEOXYADENOSINE EC50 = 1500.0 nM 5.82
CHEMBL3143525 EC50 = 8000.0 nM 5.10
CHEMBL3143553 EC50 > 10000.0 nM -
CHEMBL3142653 EC50 > 10000.0 nM -
CHEMBL3142980 EC50 > 10000.0 nM -
CHEMBL3142650 EC50 > 10000.0 nM -
CHEMBL3143549 F-ARAG EC50 > 10000.0 nM -
CHEMBL3143557 EC50 > 10000.0 nM -
CHEMBL3142654 EC50 > 10000.0 nM -
CHEMBL3142651 EC50 > 10000.0 nM -