Assay Detail
Functional
CHEMBL698755
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Effective concentration against influenza virus in MDCK cells
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | unidentified influenza virus |
| Cell Type | MDCK |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Target
unidentified influenza virus (CHEMBL613128) ↗| Type | ORGANISM |
| Organism | unidentified influenza virus |
Publication
Use of a pharmacophore model to discover a new class of influenza endonuclease inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 4.68 | 4.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL16377 | — | — | 1 | 4.68 |
| CHEMBL277536 | — | — | 1 | - |
| CHEMBL275631 | — | — | 1 | - |
| CHEMBL16239 | — | — | 1 | - |
| CHEMBL16525 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL16377 | — | EC50 | = | 21000.0 | nM | 4.68 |
| CHEMBL277536 | — | EC50 | > | 30000.0 | nM | - |
| CHEMBL275631 | — | EC50 | > | 90000.0 | nM | - |
| CHEMBL16239 | — | EC50 | > | 40000.0 | nM | - |
| CHEMBL16525 | — | EC50 | > | 100000.0 | nM | - |