Assay Detail
Functional
CHEMBL698765
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Concentration required for 50% inhibition of influenza A/WS/33 by plaque reduction assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | unidentified influenza virus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Target
unidentified influenza virus (CHEMBL613128) ↗| Type | ORGANISM |
| Organism | unidentified influenza virus |
Publication
Structure-activity relationships of carbocyclic influenza neuraminidase inhibitors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.30 | 8.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL432329 | — | — | 1 | 8.80 |
| CHEMBL55921 | — | — | 1 | 7.36 |
| CHEMBL52195 | — | — | 1 | 4.66 |
| CHEMBL54758 | — | — | 1 | 4.36 |
| CHEMBL53507 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL432329 | — | IC50 | = | 1.6 | nM | 8.80 |
| CHEMBL55921 | — | IC50 | = | 44.0 | nM | 7.36 |
| CHEMBL52195 | — | IC50 | = | 22000.0 | nM | 4.66 |
| CHEMBL54758 | — | IC50 | = | 44000.0 | nM | 4.36 |
| CHEMBL53507 | — | IC50 | - | nM | - |