Assay Detail
Functional
CHEMBL698921
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Compound was evaluated for the effect on growth and macromolecule synthesis by HeLa cells and the cell growth inhibition
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis, cell growth inhibition, and antitumor screening of 2-(p-n-butylanilino)purines and their nucleoside analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.89 | 5.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2112113 | — | — | 1 | 5.85 |
| CHEMBL2112112 | — | — | 1 | 5.30 |
| CHEMBL2112115 | — | — | 1 | 4.99 |
| CHEMBL2079564 | — | — | 1 | 4.60 |
| CHEMBL16122 | — | — | 1 | 4.40 |
| CHEMBL16193 | — | — | 1 | 4.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2112113 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL2112112 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL2112115 | — | IC50 | = | 10300.0 | nM | 4.99 |
| CHEMBL2079564 | — | IC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL16122 | — | IC50 | = | 40000.0 | nM | 4.40 |
| CHEMBL16193 | — | IC50 | = | 65000.0 | nM | 4.19 |