Assay Detail
Functional
CHEMBL698973
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Stimulation of glycogen synthase in CHO cells expressing human insulin receptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cricetulus griseus |
| Cell Type | CHO |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Synthesis and in vitro characterization of 1-(4-aminofurazan-3-yl)-5-dialkylaminomethyl-1H-[1,2,3]triazole-4-carboxylic acid derivatives. A new class of selective GSK-3 inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 5.08 | 5.73 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL326705 | — | — | 1 | 5.73 |
| CHEMBL325353 | — | — | 1 | 5.54 |
| CHEMBL113168 | — | — | 1 | 4.72 |
| CHEMBL322970 | — | — | 1 | 4.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL326705 | — | EC50 | = | 1850.0 | nM | 5.73 |
| CHEMBL325353 | — | EC50 | = | 2850.0 | nM | 5.54 |
| CHEMBL113168 | — | EC50 | = | 19070.0 | nM | 4.72 |
| CHEMBL322970 | — | EC50 | = | 45600.0 | nM | 4.34 |