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Assay Detail

CHEMBL699161

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of inositol-5-monophosphate dehydrogenase (IMPDH)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Inosine-5'-monophosphate dehydrogenase (IMPDH) (CHEMBL2111369)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

New dermatological agents for the treatment of psoriasis.
Thacher SM, Vasudevan J, Tsang KY, Nagpal S, Chandraratna RA.
J Med Chem (2001) 44 : 281 -297
PubMed 11462969 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.70 7.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL101365 1 7.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL101365 IC50 = 20.0 nM 7.70