Assay Detail
Binding
CHEMBL699162
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of inositol-5-monophosphate dehydrogenase (IMPDH); range 7-8 nM
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Target
Inosine-5'-monophosphate dehydrogenase (IMPDH) (CHEMBL2111369) ↗| Type | PROTEIN FAMILY |
| Organism | Homo sapiens |
Publication
New dermatological agents for the treatment of psoriasis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.15 | 8.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL304087 | MERIMEPODIB | 2.0 | 1 | 8.15 |
| CHEMBL101754 | — | — | 1 | 8.15 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL304087 | MERIMEPODIB | IC50 | = | 7.0 | nM | 8.15 |
| CHEMBL101754 | — | IC50 | = | 7.0 | nM | 8.15 |