Assay Detail
Functional
CHEMBL699285
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In vitro inhibition of cholesterol synthesis in HepG2 cells.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HepG2 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Design and synthesis of new hypocholesterolemic organosilanes with antioxidant properties
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.81 | 6.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL108692 | — | — | 1 | 6.92 |
| CHEMBL434507 | — | — | 1 | 6.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL108692 | — | IC50 | = | 120.0 | nM | 6.92 |
| CHEMBL434507 | — | IC50 | = | 200.0 | nM | 6.70 |