Assay Detail
Functional
CHEMBL699494
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Inhibition of 10 uM ADP-induced human gel filtered platelet aggregation with 0.1 mg/mL human fibrinogen
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Non-peptide fibrinogen receptor antagonists. 4. Proposed three-dimensional requirements in centrally constrained inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.60 | 4.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL32960 | — | — | 1 | 4.60 |
| CHEMBL53275 | — | — | 1 | - |
| CHEMBL299947 | — | — | 1 | - |
| CHEMBL54842 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL32960 | — | IC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL53275 | — | IC50 | = | 330000.0 | nM | - |
| CHEMBL299947 | — | IC50 | = | 10000000.0 | nM | - |
| CHEMBL54842 | — | IC50 | = | 2300000.0 | nM | - |