Assay Detail
Functional
CHEMBL699628
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Tested in vitro for inhibitory effect on the growth of K-562 cell line
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | K562 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Shikonin derivatives: synthesis and inhibition of human telomerase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.60 | 4.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL28446 | — | — | 1 | 4.75 |
| CHEMBL403516 | ACETYLSHIKONIN | — | 1 | 4.54 |
| CHEMBL416387 | — | — | 1 | 4.51 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL28446 | — | IC50 | = | 18000.0 | nM | 4.75 |
| CHEMBL403516 | ACETYLSHIKONIN | IC50 | = | 29000.0 | nM | 4.54 |
| CHEMBL416387 | — | IC50 | = | 31000.0 | nM | 4.51 |