Assay Detail
Binding
CHEMBL699731
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Inhibition of Inositol 1,4,5-trisphosphate 3-kinase (IP3K) from rat brain
6
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Molecular interactions of all possible regioisomers of synthetic myo-inositol phosphates with inositol 1,4,5-trisphosphate 3-kinase
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.64 | 5.45 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL279107 | INS(1,4,5)P3 | — | 2 | 5.45 |
| CHEMBL23552 | — | — | 4 | 4.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL279107 | INS(1,4,5)P3 | IC50 | = | 3550.0 | nM | 5.45 |
| CHEMBL279107 | INS(1,4,5)P3 | IC50 | = | 12400.0 | nM | 4.91 |
| CHEMBL23552 | — | IC50 | = | 42100.0 | nM | 4.38 |
| CHEMBL23552 | — | IC50 | = | 56700.0 | nM | 4.25 |
| CHEMBL23552 | — | IC50 | = | 65200.0 | nM | 4.19 |
| CHEMBL23552 | — | IC50 | = | 220000.0 | nM | - |