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Assay Detail

CHEMBL699735

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Inositol 1,4,5-trisphosphate 3-kinase from rat brain homogenate (r-metabolically resistant)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Tissue Brain
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Deoxygenated inositol 1,4,5-trisphosphate analogues and their interaction with metabolic enzymes. (1R,2R,4R)-cyclohexane-1,2,4-tris(methylenesulfonate): a potent selective 5-phosphatase inhibitor.
Kozikowski AP, Ognyanov VI, Chen C, Fauq AH, Safrany ST, Wilcox RA, Nahorski SR.
J Med Chem (1993) 36 : 3035 -3038
PubMed 8411022 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 4.44 4.44

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1160801 1 4.44

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1160801 Ki = 36000.0 nM 4.44