Assay Detail

CHEMBL700266

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Cytotoxic activity against K562 erythroleukemic cells

ChEMBL ↗

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Target

K562 (CHEMBL385) ↗

Open DB target context

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Primary target K562

CHEMBL385

Anchored from Assay target.

Protein identity K562

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Cell Type	K562
Confidence	1 — Organism
Curated By	Intermediate

Target

K562 (CHEMBL385) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Solution structure of iron(III)-anthracycline complexes.

Fiallo MM, Drechsel H, Garnier-Suillerot A, Matzanke BF, Kozlowski H.
J Med Chem (1999) 42 : 2844 -2851
PubMed 10425093 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	8.70	8.70

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL1117	IDARUBICIN	4.0	1	8.70

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL1117	IDARUBICIN	IC50	=	2.0	nM	8.70