Assay Detail
Functional
CHEMBL700749
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested for cytotoxicity against the growth of human gastric carcinoma cell line ( KATO III ).
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | KATO III |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
New neplanocin analogues. 12. Alternative synthesis and antimalarial effect of (6'R)-6'-C-methylneplanocin A, a potent AdoHcy hydrolase inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.31 | 6.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL8771 | NEOPLANOCIN A | — | 1 | 6.66 |
| CHEMBL327105 | — | — | 1 | 5.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL8771 | NEOPLANOCIN A | IC50 | = | 220.0 | nM | 6.66 |
| CHEMBL327105 | — | IC50 | = | 1100.0 | nM | 5.96 |