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Assay Detail

CHEMBL701015

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of JNK2-alpha-2 kinase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Expert

Target

Mitogen-activated protein kinase 9 (CHEMBL4179)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Pyridazine based inhibitors of p38 MAPK.
McIntyre CJ, Ponticello GS, Liverton NJ, O'Keefe SJ, O'Neill EA, Pang M, Schwartz CD, Claremon DA.
Bioorg Med Chem Lett (2002) 12 : 689 -692
PubMed 11844702 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.85 5.85

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL162295 1 5.85

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL162295 IC50 = 1400.0 nM 5.85