Assay Detail
Binding
CHEMBL701115
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Inhibitory activity against 3'-processing of DNA by HIV-1 integrase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Human immunodeficiency virus type 1 integrase (CHEMBL3471) ↗| Type | SINGLE PROTEIN |
| Organism | Human immunodeficiency virus 1 |
Publication
Coumarin-based inhibitors of HIV integrase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.07 | 4.09 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL84340 | — | — | 1 | 4.09 |
| CHEMBL310585 | — | — | 1 | 4.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL84340 | — | IC50 | = | 81000.0 | nM | 4.09 |
| CHEMBL310585 | — | IC50 | = | 89000.0 | nM | 4.05 |