Assay Detail
Binding
CHEMBL701164
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested in vitro to inhibit human immuno virus-1 (HIV-1) using enzymatic disintegration assay.
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Human immunodeficiency virus type 1 protease (CHEMBL243) ↗| Type | SINGLE PROTEIN |
| Organism | Human immunodeficiency virus 1 |
Publication
Modeling of the inhibition of retroviral integrases by styrylquinoline derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.47 | 5.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL59548 | — | — | 1 | 5.57 |
| CHEMBL40148 | — | — | 1 | 5.47 |
| CHEMBL418613 | — | — | 1 | 5.38 |
| CHEMBL61203 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL59548 | — | IC50 | = | 2700.0 | nM | 5.57 |
| CHEMBL40148 | — | IC50 | = | 3400.0 | nM | 5.47 |
| CHEMBL418613 | — | IC50 | = | 4200.0 | nM | 5.38 |
| CHEMBL61203 | — | IC50 | > | 100000.0 | nM | - |