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Assay Detail

CHEMBL701261

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was tested for inhibitory activity against the in vitro growth of MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type KB
Confidence 1 — Organism
Curated By Intermediate

Target

KB (CHEMBL398)
Type CELL-LINE
Organism Homo sapiens

Publication

Nucleosides and nucleotides. 180. Synthesis and antitumor activity of nucleosides that have a hydroxylamino group instead of a hydroxyl group at the 2'- or 3'-position of the sugar moiety.
Ogawa A, Tanaka M, Sasaki T, Matsuda A.
J Med Chem (1998) 41 : 5094 -5107
PubMed 9836625 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.70 5.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL347737 1 5.70
CHEMBL149829 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL347737 IC50 = 1990.0 nM 5.70
CHEMBL149829 IC50 > 300000.0 nM -