Assay Detail

CHEMBL701378

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Functional

Inhibition of [3H]diltiazem binding to L-type calcium channel of rabbit skeletal muscle

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

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Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Oryctolagus cuniculus
Tissue	Muscle tissue
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Piperidine-ether based hNK1 antagonists 2: Investigation of the effect of N-substitution

Harrison T, Owens A, Williams B, Swain C, Baker R, Hutson P, Sadowski S, Cascieri M
Bioorg Med Chem Lett (1995) 5 : 209 -212
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.12	6.12

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL27006	—	—	1	6.12

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL27006	—	IC50	=	760.0	nM	6.12