Assay Detail
Binding
CHEMBL701762
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Inhibitory concentration of compound was determined against kallikrein
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
1-(2-Naphthyl)-1H-pyrazole-5-carboxylamides as potent factor Xa inhibitors. Part 2: A survey of P4 motifs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.01 | 5.01 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL277949 | — | — | 1 | 5.01 |
| CHEMBL20934 | — | — | 1 | - |
| CHEMBL20766 | — | — | 1 | - |
| CHEMBL20604 | — | — | 1 | - |
| CHEMBL281175 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL277949 | — | IC50 | = | 9700.0 | nM | 5.01 |
| CHEMBL20934 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL20766 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL20604 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL281175 | — | IC50 | > | 10000.0 | nM | - |