Assay Detail
Functional
CHEMBL701865
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In vitro inhibition of L1210 cell growth in culture.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L1210 |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
Quinazoline antifolate thymidylate synthase inhibitors: heterocyclic benzoyl ring modifications.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.01 | 7.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL434209 | — | — | 1 | 7.05 |
| CHEMBL40321 | — | — | 1 | 6.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL434209 | — | IC50 | = | 90.0 | nM | 7.05 |
| CHEMBL40321 | — | IC50 | = | 110.0 | nM | 6.96 |