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Assay Detail

CHEMBL701866

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
In vitro cytotoxicity was evaluated in L1210 cell line
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type L1210
Confidence 1 — Organism
Curated By Intermediate

Target

L1210 (CHEMBL386)
Type CELL-LINE
Organism Mus musculus

Publication

Design and synthesis of novel chrysene-linked pyrrolo[2,1-c][1,4]-benzodiazepine hybrids as potential DNA-binding agents.
Kamal A, Ramesh G, Ramulu P, Srinivas O, Rehana T, Sheelu G.
Bioorg Med Chem Lett (2003) 13 : 3451 -3454
PubMed 14505647 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.42 6.42

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL293096 1 6.42

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL293096 IC50 = 380.0 nM 6.42